Pub. Date : 2015 Feb
PMID : 25533241
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-alpha initiated p38 MAPK and NF-kappaB pathways. | pristane | toll-like receptor 3 | Rattus norvegicus |
| 2 | Based on pristane-induced arthritis (PIA), we found that T cells mediate TLR3 overexpression in fibroblast-like synoviocytes (FLS). | pristane | toll-like receptor 3 | Rattus norvegicus |
| 3 | Rat FLS were co-cultured with pristane primed T cell conditioned medium (PPT medium), and TLR3 expression of FLS was significantly induced. | pristane | toll-like receptor 3 | Rattus norvegicus |
| 4 | Summarily, TNF-alpha derived from pristane primed T cells induced TLR3 expression of FLS through activating p38 MAPK and NF-kappaB pathways. | pristane | toll-like receptor 3 | Rattus norvegicus |