| Protein Name | toll-like receptor 3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 364594 |
| Gene Symbol | Tlr3 |
| UniProt | F1LN63 (F1LN63_RAT), Q7TNI8 (Q7TNI8_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
51
Total Number of Articles : 58 |
Description |
toll-like receptor 3 |
| Gene Summary |
Enables double-stranded RNA binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to exogenous dsRNA; and microglial cell activation. Located in cell surface. Used to study asthma. Biomarker of colitis; pancreatitis; perinatal necrotizing enterocolitis; peripheral nervous system disease; and pre-eclampsia. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; liver disease (multiple); and primary immunodeficiency disease (multiple). Orthologous to human TLR3 (toll like receptor 3). [provided by Alliance of Genome Resources, Jul 2025] |
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