Title : Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists.

Pub. Date : 2015 Jun

PMID : 25532870






2 Functional Relationships(s)
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1 Carbaryl, 2-methylindole, and 3-methylindole induced the highest CYP1A activity in zebrafish. Skatole cytochrome P450, family 1, subfamily A Danio rerio
2 However, CYP1A knockdown in phenanthrene and 3-methylindole only moderately increased pericardial edema relative to coexposure to FL. Skatole cytochrome P450, family 1, subfamily A Danio rerio