Protein Name cytochrome P450, family 1, subfamily A
Organism Danio rerio
Gene ID 140634
Gene Symbol

cyp1a

UniProt Q8UW07 (Q8UW07_DANRE)
Relationships Total Number of functionally related compound(s) : 106
Total Number of Articles : 114
Description

cytochrome P450, family 1, subfamily A

Gene Summary

Predicted to enable monooxygenase activity. Acts upstream of or within cellular aromatic compound metabolic process; cellular response to organic cyclic compound; and cellular response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including digestive system; pectoral fin bud; pericardial region; tail bud; and vasculature. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to several human genes including CYP1A1 (cytochrome P450 family 1 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 1A1
  • cytochrome P450, subfamily I, polypeptide 1
  • cyp1a1
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Properties