Pub. Date : 2015 Feb
PMID : 25527205
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells. | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 2 | Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells. | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 3 | RESULTS: These results showed that oxymatrine inhibited the proliferation and invasion of gastric cells through inhibition of EGFR/Cyclin D1/CDK4/6, EGFR/Akt and MEK-1/ERK1/2/MMP2 pathway by inhibiting EGFR(p-Tyr845). | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 4 | RESULTS: These results showed that oxymatrine inhibited the proliferation and invasion of gastric cells through inhibition of EGFR/Cyclin D1/CDK4/6, EGFR/Akt and MEK-1/ERK1/2/MMP2 pathway by inhibiting EGFR(p-Tyr845). | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 5 | RESULTS: These results showed that oxymatrine inhibited the proliferation and invasion of gastric cells through inhibition of EGFR/Cyclin D1/CDK4/6, EGFR/Akt and MEK-1/ERK1/2/MMP2 pathway by inhibiting EGFR(p-Tyr845). | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 6 | CONCLUSION: Oxymatrine effectively suppressed the phosphorylation of EGFR (Tyr845), and EGFR was the target of oxymatrine. | oxymatrine | epidermal growth factor receptor | Homo sapiens |
| 7 | CONCLUSION: Oxymatrine effectively suppressed the phosphorylation of EGFR (Tyr845), and EGFR was the target of oxymatrine. | oxymatrine | epidermal growth factor receptor | Homo sapiens |