Pub. Date : 2015 Apr
PMID : 25515945
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The impact of activity of the genes encoding CYP3A4, CYP3A5, and CYP2C9 on the pharmacokinetics of voriconazole cannot be ignored because, second to CYP2C19, they are the most important enzymes involved in voriconazole metabolism. | Voriconazole | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | The impact of activity of the genes encoding CYP3A4, CYP3A5, and CYP2C9 on the pharmacokinetics of voriconazole cannot be ignored because, second to CYP2C19, they are the most important enzymes involved in voriconazole metabolism. | Voriconazole | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | The influence of genetic polymorphisms in CYP3A4, CYP3A5, and CYP2C9 on the plasma concentrations of voriconazole was evaluated in the present study. | Voriconazole | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |