Title : Identification of tetrahydrocarbazoles as novel multifactorial drug candidates for treatment of Alzheimer's disease.

Pub. Date : 2014 Dec 16

PMID : 25514752






1 Functional Relationships(s)
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1 We found that the tetrahydrocarbazole lead structure, first, dampens the enhanced calcium release from ER in HEK293 cells expressing familial Alzheimer"s disease (FAD)-linked presenilin 1 mutations. 2,3,4,9-tetrahydro-1H-carbazole epiregulin Homo sapiens