Title : Testosterone reduces AGTR1 expression to prevent β-cell and islet apoptosis from glucotoxicity.

Pub. Date : 2015 Mar

PMID : 25512346






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Testosterone significantly reduced expression of AGTR1 protein in INS-1 cells cultured in high-glucose medium or high-glucose medium with Ang II. Glucose angiotensin II receptor, type 1a Rattus norvegicus
2 Testosterone significantly reduced expression of AGTR1 protein in INS-1 cells cultured in high-glucose medium or high-glucose medium with Ang II. Glucose angiotensin II receptor, type 1a Rattus norvegicus
3 Testosterone decreased the expression of AGTR1 and p47(phox) mRNA and protein in comparison with levels in cells cultured in high-glucose medium alone. Glucose angiotensin II receptor, type 1a Rattus norvegicus