Title : Identification of metabolic pathways and enzyme systems involved in the in vitro human hepatic metabolism of dronedarone, a potent new oral antiarrhythmic drug.

Pub. Date : 2014 Jun

PMID : 25505590






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP3A isoforms mostly contributed to N-debutylation while hydroxylation on the butyl-benzofuran moiety was catalyzed by CYP2D6. Nitrogen cytochrome P450 family 3 subfamily A member 4 Homo sapiens