Title : A high cell density transient transfection system for therapeutic protein expression based on a CHO GS-knockout cell line: process development and product quality assessment.

Pub. Date : 2015 May

PMID : 25502369






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 By creating a bi-allelic glutamine synthetase knock out of the original CHOK1SV host cell line, they were able to improve the efficiency of generating high producing stable CHO lines for drug product manufacturing. CAV protocol glutamine synthetase Cricetulus griseus