Title : ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.

Pub. Date : 2015 Jan 22

PMID : 25498912






1 Functional Relationships(s)
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1 We evaluated the role of 3 alpha(2,3)sialyltransferases, ST3Gal-3, -4, and -6, which act on the type II N-Acetyllactosamine structure (Galbeta1,4GlcNAc) to create sialyl Lewis-X (sLe(X)) and related sialofucosylated glycans on human leukocytes of myeloid lineage. N-acetyllactosamine ST3 beta-galactoside alpha-2,3-sialyltransferase 3 Homo sapiens