Pub. Date : 2015 Feb 3
PMID : 25496994
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Furthermore, the c-Jun N-terminal protein kinase (JNK) is required for rotenone-induced dopamine neuron death. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
3 | Furthermore, the c-Jun N-terminal protein kinase (JNK) is required for rotenone-induced dopamine neuron death. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
4 | Treatment with taxol, a microtubule stabilizing agent, attenuates rotenone-induced phosphorylation and presumably activation of JNK. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |
5 | This suggests that JNK is activated by microtubule destabilization upon rotenone exposure. | Rotenone | mitogen-activated protein kinase 8 | Homo sapiens |