Pub. Date : 2015 Apr
PMID : 25487615
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | (-)-Epigallocatechin-3-gallate inhibits nasopharyngeal cancer stem cell self-renewal and migration and reverses the epithelial-mesenchymal transition via NF-kappaB p65 inactivation. | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 2 | Epigallocatechin-3-gallate (EGCG) inhibits cancer progression by attenuating NF-kappaB p65 activity, which is upregulated in CSCs and plays an important role in epithelial-mesenchymal transition (EMT). | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 3 | Epigallocatechin-3-gallate (EGCG) inhibits cancer progression by attenuating NF-kappaB p65 activity, which is upregulated in CSCs and plays an important role in epithelial-mesenchymal transition (EMT). | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 4 | Moreover, EGCG inhibited NF-kappaB p65 activity by modulating the cellular localization of p65 and decreasing the transcriptional regulation of NF-kappaB p65 on Twist1 expression. | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 5 | Moreover, EGCG inhibited NF-kappaB p65 activity by modulating the cellular localization of p65 and decreasing the transcriptional regulation of NF-kappaB p65 on Twist1 expression. | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 6 | Moreover, EGCG inhibited NF-kappaB p65 activity by modulating the cellular localization of p65 and decreasing the transcriptional regulation of NF-kappaB p65 on Twist1 expression. | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |
| 7 | NF-kappaB p65 is a novel therapeutic target in NPCSCs, and the inhibition of activated NF-kappaB p65 in CSCs by EGCG may offer an effective treatment for NPC. | epigallocatechin gallate | RELA proto-oncogene, NF-kB subunit | Homo sapiens |