Pub. Date : 2015 May
PMID : 25482158
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Based on mutations in CTE patients, an in vivo mouse model was developed, with tamoxifen-inducible deletion of exon 4 in Epcam resulting in mutant protein with decreased expression. | Tamoxifen | epithelial cell adhesion molecule | Mus musculus |
| 2 | Tamoxifen treatment of Epcam (Delta4/Delta4) mice resulted in pathological features of villous atrophy and epithelial tufts, similar to those in human CTE patients, within 4 days post induction. | Tamoxifen | epithelial cell adhesion molecule | Mus musculus |
| 3 | Tamoxifen-treated Epcam (Delta4/Delta4) mice demonstrated pathological features. | Tamoxifen | epithelial cell adhesion molecule | Mus musculus |