Title : Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics.

Pub. Date : 2015 Jan 5

PMID : 25466967






1 Functional Relationships(s)
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Protein Name
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1 Affinity of TC to the uptake transporters OATP1A2, -1B1, -1B3, -2B1, OCT1, -2, -3, OCTN2, NTCP, and ASBT and the efflux carriers P-gp, MRP2 and MRP3 transfected in HEK293 and MDCK2 cells was measured. trospium chloride solute carrier family 10 member 2 Homo sapiens