Title : Brown algae phlorotannins enhance the tumoricidal effect of cisplatin and ameliorate cisplatin nephrotoxicity.

Pub. Date : 2015 Feb

PMID : 25462204






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1 CONCLUSION: These data suggest that brown algae phlorotannins may improve the efficacy of platinum drugs for ovarian cancer by enhancing cancer cell apoptosis via the ROS/Akt/NFkappaB pathway and reduce nephrotoxicity by protecting against normal kidney cell damage. Platinum nuclear factor kappa B subunit 1 Homo sapiens