Title : In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.

Pub. Date : 2015 Apr

PMID : 25451157






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GSK5182 N-demethylation and hydroxylation is mainly mediated by CYP3A4, whereas FMO1 and FMO3 contribute to the formation of GSK5182 N-oxide from GSK5182. GSK5182 cytochrome P450 family 3 subfamily A member 4 Homo sapiens