Title : Lipoprotein internalisation induced by oncogenic AMPK activation is essential to maintain glioblastoma cell growth.

Pub. Date : 2014 Dec

PMID : 25450947

1 Functional Relationships(s)
Compound Name
Protein Name
1 RESULTS: We show that the high levels of activated AMPK, observed in astrocytic tumours, increase extracellular lipid internalisation and reduce energy expenditure by inhibiting "de novo" fatty acid (FA) synthesis, which allows tumour cells to obtain building blocks and energy to be able to create new organelles and new cells. Fatty Acids protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens