Title : Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial-mesenchymal transition.

Pub. Date : 2015 Jan 28

PMID : 25449432






1 Functional Relationships(s)
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1 Furthermore, pantoprazole treatment resulted in a profound reduction of both total and phosphorylated forms of Akt and GSK-3beta, which in turn suppressed the adriamycin-induced Wnt/beta-catenin signaling in SGC7901/ADR cells. Doxorubicin glycogen synthase kinase 3 beta Homo sapiens