Title : BDNF contributes to the development of neuropathic pain by induction of spinal long-term potentiation via SHP2 associated GluN2B-containing NMDA receptors activation in rats with spinal nerve ligation.

Pub. Date : 2015 Jan

PMID : 25447233






1 Functional Relationships(s)
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1 Taken together, these results suggest that the BDNF/SHP2/GluN2B-NMDA signaling cascade plays a vital role in the development of central sensitization and neuropathic pain after peripheral nerve injury. N-Methylaspartate brain-derived neurotrophic factor Rattus norvegicus