Title : Downregulation of adipose triglyceride lipase promotes cardiomyocyte hypertrophy by triggering the accumulation of ceramides.

Pub. Date : 2015 Jan 1

PMID : 25436917






1 Functional Relationships(s)
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1 Moreover, the accumulation of ceramide was due to elevation of free fatty acids in ATGL-knockdown cardiomyocytes, which could be explained by the reduced activity of peroxisome proliferator-activated receptor (PPAR) alpha leading to imbalance of fatty acid uptake and oxidation. Fatty Acids, Nonesterified peroxisome proliferator activated receptor alpha Mus musculus