Pub. Date : 2012 Apr
PMID : 25436707
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Abstract Successive action of cytochrome P450-7B1 (CYP7B1) and 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) on 3beta-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7beta-hydroxylated derivatives. | Dehydroepiandrosterone | cytochrome P450 family 7 subfamily B member 1 | Homo sapiens |
| 2 | Abstract Successive action of cytochrome P450-7B1 (CYP7B1) and 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) on 3beta-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7beta-hydroxylated derivatives. | Dehydroepiandrosterone | cytochrome P450 family 7 subfamily B member 1 | Homo sapiens |
| 3 | As low doses of the 7beta-hydroxylated derivatives of DHEA and epiandrosterone trigger the resolution of inflammation and tissue repair, CYP7B1 and 11beta-HSD1 tissue contents may reflect the tissue ability for reparation after pathological conditions. | Dehydroepiandrosterone | cytochrome P450 family 7 subfamily B member 1 | Homo sapiens |