Title : The roles of protein kinase C and cyclic nucleotide dependent kinase in signal transduction in human interferon gamma induction by poly I:poly C.

Pub. Date : 1989 May 8

PMID : 2542091






2 Functional Relationships(s)
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1 Significant enhancement of IFN gamma production by poly(I):poly(C) is observed in the presence of the phorbol ester, 12-O-tetradecanoylphorbol 13-acetate (TPA, a protein kinase C (PKC) activator). Poly C plasminogen activator, tissue type Homo sapiens
2 The level of activation of PKC is quite remarkable in the case of the combined stimulation by poly(I):poly(C) and TPA as compared to poly(I):poly(C) alone. Poly C plasminogen activator, tissue type Homo sapiens