Title : Predicting 5-fluorouracil toxicity: DPD genotype and 5,6-dihydrouracil:uracil ratio.

Pub. Date : 2014 Sep

PMID : 25410891






2 Functional Relationships(s)
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1 Predicting 5-fluorouracil toxicity: DPD genotype and 5,6-dihydrouracil:uracil ratio. Uracil dihydropyrimidine dehydrogenase Homo sapiens
2 Here, we evaluated the baseline (pretherapeutic) plasma 5,6-dihydrouracil:uracil (UH2:U) ratio as a marker of DPD activity in the context of DPYD genotypes. Uracil dihydropyrimidine dehydrogenase Homo sapiens