Title : Protective effects of caffeic acid against hypothalamic neuropeptides alterations induced by malathion in rat.

Pub. Date : 2015 Apr

PMID : 25404496






3 Functional Relationships(s)
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1 Furthermore, we used in silico analysis, known as computational docking, to highlight the nature of acetylcholinesterase-malathion/caffeic acid interactions. caffeic acid acetylcholinesterase Rattus norvegicus
2 We suggest that caffeic acid can interact with acetylcholinesterase as the primary target of organophosphorus compounds. caffeic acid acetylcholinesterase Rattus norvegicus
3 Results predict that caffeic acid can block partly the acetylcholinesterase gorge entrance via pi-pi stacking interaction with Tyr 124 and Trp 286 residues of the peripheral site leading to its stricture. caffeic acid acetylcholinesterase Rattus norvegicus