Title : Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway.

Pub. Date : 2014 Dec 15

PMID : 25401518






4 Functional Relationships(s)
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1 In this study, Wnt5A was found to be significantly upregulated in MES-SA/Dx5 and MCF7/ADR2 cells, suggesting an important role for the Wnt5A signaling pathway in cancer drug resistance. 2-(N-morpholino)ethanesulfonic acid Wnt family member 5A Homo sapiens
2 In this study, Wnt5A was found to be significantly upregulated in MES-SA/Dx5 and MCF7/ADR2 cells, suggesting an important role for the Wnt5A signaling pathway in cancer drug resistance. 2-(N-morpholino)ethanesulfonic acid Wnt family member 5A Homo sapiens
3 However, expression of Wnt target genes and CRE activities was downregulated in Wnt5A shRNA stably-transfected MES-SA/Dx5 cells. 2-(N-morpholino)ethanesulfonic acid Wnt family member 5A Homo sapiens
4 However, expression of Wnt target genes and CRE activities was downregulated in Wnt5A shRNA stably-transfected MES-SA/Dx5 cells. 2-(N-morpholino)ethanesulfonic acid Wnt family member 5A Homo sapiens