Title : Protective role of the cholinergic anti-inflammatory pathway in a mouse model of viral myocarditis.

Pub. Date : 2014

PMID : 25396421






2 Functional Relationships(s)
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1 Because nicotine is a alpha7nAchR agonist and methyllycaconitine is a alpha7nAchR antagonist, we conclude that alpha7nAchR activation increases the phosphorylation of STAT3, reduces the expression of TNF-alpha and IL-6, and, ultimately, alleviates viral myocarditis. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Because nicotine is a alpha7nAchR agonist and methyllycaconitine is a alpha7nAchR antagonist, we conclude that alpha7nAchR activation increases the phosphorylation of STAT3, reduces the expression of TNF-alpha and IL-6, and, ultimately, alleviates viral myocarditis. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus