Title : Effects of silica exposure on the cardiac and renal inflammatory and fibrotic response and the antagonistic role of interleukin-1 beta in C57BL/6 mice.

Pub. Date : 2016 Feb

PMID : 25388157






1 Functional Relationships(s)
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1 The real-time PCR studies showed that (1) inhalational silica induced inflammatory responses in the heart and kidney by elevated mRNA levels of TNF-alpha, IL-6 and MCP-1; (2) early fibrotic responses in the heart were observed as elevated mRNA levels of collagen I and fibronectin. Silicon Dioxide fibronectin 1 Mus musculus