Title : Epoxidation activities of human cytochromes P450c17 and P450c21.

Pub. Date : 2014 Dec 9

PMID : 25386927






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP17A1 wild-type and mutation A105L do not 21- or 16alpha-hydroxylate pregnenolone, but the enzymes 21-hydroxylated and 16alpha,17-epoxidized 16,17-dehydropregnenolone (pregna-5,16-diene-3beta-ol-20-one) in 4:1 or 12:1 ratios, respectively. pregna-5,16-diene-3beta-ol-20-one cytochrome P450 family 17 subfamily A member 1 Homo sapiens