Title : Hyperinsulinemia induces hepatic iron overload by increasing liver TFR1 via the PI3K/IRP2 pathway.

Pub. Date : 2014 Dec

PMID : 25385842






2 Functional Relationships(s)
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1 Hyperinsulinemia induces hepatic iron overload by increasing liver TFR1 via the PI3K/IRP2 pathway. Iron transferrin receptor Rattus norvegicus
2 In conclusion, the findings of this study indicate that hyperinsulnemia could induce hepatic iron overload by upregulating liver TFR1 via the PI3K/AKT/mTOR/IRP2 pathway, which may be one of the main reasons for the occurrence of DIOS. Iron transferrin receptor Rattus norvegicus