Title : Possible Role of Raf-1 Kinase in the Development of Cerebral Vasospasm and Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats.

Pub. Date : 2015 Dec

PMID : 25367879






2 Functional Relationships(s)
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1 In addition, BAY 43-9006 treatment significantly reversed the phosphorylation of ERK1/2 and the activation of NF-kappaB induced by SAH and decreased the messenger RNA (mRNA) levels of IL-6 and IL-1beta. Sorafenib mitogen activated protein kinase 3 Rattus norvegicus
2 Besides, BAY 43-9006 inhibited the phosphorylation of Raf-1 and ERK1/2; decreased the protein levels of COX-2, VEGF, and MMP-9; and reversed the activation of NF-kappaB induced by SAH. Sorafenib mitogen activated protein kinase 3 Rattus norvegicus