Pub. Date : 2015 Jan
PMID : 25359531
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Injection of corticotropin-releasing hormone into the amygdala aggravates visceral nociception and induces noradrenaline release in rats. | Norepinephrine | corticotropin releasing hormone | Rattus norvegicus |
2 | Here, we verified the hypothesis that CRH in the CeA sensitizes visceral nociception via CRH-R1 with release of noradrenaline, dopamine, and serotonin (5-HT) in the CeA. | Norepinephrine | corticotropin releasing hormone | Rattus norvegicus |
3 | Noradrenaline in the CeA was increased by CRD, further increased by CRH, and inhibited by CRH-R1 antagonist. | Norepinephrine | corticotropin releasing hormone | Rattus norvegicus |
4 | CONCLUSIONS & INFERENCES: These results suggest that CRH in the CeA sensitizes visceral nociception via CRH-R1 with release of noradrenaline. | Norepinephrine | corticotropin releasing hormone | Rattus norvegicus |