Title : Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition.

Pub. Date : 2015 Jan 1

PMID : 25348515






2 Functional Relationships(s)
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1 CBL knockdown increased PDAC resistance to gemcitabine and 5-fluorouracil (5-FU) by upregulating pEGFR (Y1068), pERK, and pAKT. Fluorouracil Cbl proto-oncogene Homo sapiens
2 CBL knockdown increased PDAC resistance to gemcitabine and 5-fluorouracil (5-FU) by upregulating pEGFR (Y1068), pERK, and pAKT. Fluorouracil Cbl proto-oncogene Homo sapiens