Title : Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.

Pub. Date : 2015 Jan

PMID : 25344585






1 Functional Relationships(s)
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1 Thus, therapeutic regimens with As2O3 will need to include inhibitors of both the mTOR and RSK pathways in combination to prevent engagement of negative feedback loops and maximize antineoplastic responses. Arsenic Trioxide mechanistic target of rapamycin kinase Homo sapiens