Title : An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.

Pub. Date : 2014 Oct

PMID : 25329472






1 Functional Relationships(s)
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Protein Name
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1 AGEF-1 is homologous to the mammalian BIG1 and BIG2 Arf GTPase guanine nucleotide exchange factors (GEFs), which regulate secretory traffic between the Trans-Golgi network, endosomes and the plasma membrane via activation of Arf GTPases and recruitment of the AP-1 clathrin adaptor complex. Guanine Nucleotides ADP ribosylation factor guanine nucleotide exchange factor 1 Homo sapiens