Title : Clinical outcomes in pancreatic adenocarcinoma associated with BRCA-2 mutation.

Pub. Date : 2015 Feb

PMID : 25304989






1 Functional Relationships(s)
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1 Recent reports have suggested that in the setting of impaired DNA repair, chemotherapeutic agents that induce DNA damage, such as platinum-based antineoplastic drugs (platins) and poly(ADP-ribose) polymerase inhibitors (PARP inhibitors), have improved efficacy. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens