Pub. Date : 2014 Sep 29
PMID : 25299839
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, we evaluated the protective effect of bixin on liver damage induced by carbon tetrachloride (CCl4) in rats. | bixin | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 2 | Bixin prevented the liver damage caused by CCl4, as noted by the significant decrease in serum aminotransferases release. | bixin | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 3 | Bixin protected the liver against the oxidizing effects of CCl4 by preventing a decrease in glutathione reductase activity and the levels of reduced glutathione and NADPH. | bixin | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 4 | CONCLUSION: Therefore, we can conclude that the protective effect of bixin against hepatotoxicity induced by CCl4 is related to the antioxidant activity of the compound. | bixin | C-C motif chemokine ligand 4 | Rattus norvegicus |