Pub. Date : 2014
PMID : 25299054
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Higher prevalence of metformin-induced vitamin B12 deficiency in sulfonylurea combination compared with insulin combination in patients with type 2 diabetes: a cross-sectional study. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
2 | Long-term and high-dose treatment with metformin is known to be associated with vitamin B12 deficiency in patients with type 2 diabetes. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
3 | We investigated whether the prevalence of B12 deficiency was different in patients treated with different combination of hypoglycemic agents with metformin during the same time period. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
4 | The prevalence of vitamin B12 deficiency in the metformin-treated patients was significantly higher in the S+M group compared with the I+M group (17.4% vs. 4.2%, P = 0.001). | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
5 | In conclusion, our study demonstrated that patients with type 2 diabetes who were treated with metformin combined with sulfonylurea require clinical attention for vitamin B12 deficiency and regular monitoring of their vitamin B12 levels. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |
6 | In conclusion, our study demonstrated that patients with type 2 diabetes who were treated with metformin combined with sulfonylurea require clinical attention for vitamin B12 deficiency and regular monitoring of their vitamin B12 levels. | Metformin | NADH:ubiquinone oxidoreductase subunit B3 | Homo sapiens |