Title : A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance.

Pub. Date : 2014 Nov 28

PMID : 25296283






1 Functional Relationships(s)
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1 In this communication we describe CD, UV, electrophoretic and biochemical investigations concerning thrombin binding aptamer analogues containing one or two inversions of polarity sites at the oligonucleotide ends. Oligonucleotides coagulation factor II, thrombin Homo sapiens