Title : The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients.

Pub. Date : 2015 Apr

PMID : 25287072






2 Functional Relationships(s)
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1 The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Tacrolimus, a dual substrate of CYP3A4 and CYP3A5 has a narrow therapeutic index and is characterized by high between-subject variability in oral bioavailability. Tacrolimus cytochrome P450 family 3 subfamily A member 4 Homo sapiens