Pub. Date : 2014
PMID : 25285521
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We subsequently assessed the combined influence of genetics and diet (daily intake of protein, fat and soy isoflavones) on IGF-1 and IGFBP-3 levels. | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 2 | RESULTS: Among women aged less than 50 years, circulating IGF-1 serum levels were significantly lower for those with CC genotype for IGF-1 rs1520220 than levels for those with the GC or GG genotypes (in recessive model: P = 0.007).In gene-diet analyses among these women, we found carrying CC genotype for IGF-1 rs1520220 and high soy isoflavone intake tend to be associated with lower circulating IGF-1 levels synthetically (P = 0.002). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 3 | RESULTS: Among women aged less than 50 years, circulating IGF-1 serum levels were significantly lower for those with CC genotype for IGF-1 rs1520220 than levels for those with the GC or GG genotypes (in recessive model: P = 0.007).In gene-diet analyses among these women, we found carrying CC genotype for IGF-1 rs1520220 and high soy isoflavone intake tend to be associated with lower circulating IGF-1 levels synthetically (P = 0.002). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 4 | RESULTS: Among women aged less than 50 years, circulating IGF-1 serum levels were significantly lower for those with CC genotype for IGF-1 rs1520220 than levels for those with the GC or GG genotypes (in recessive model: P = 0.007).In gene-diet analyses among these women, we found carrying CC genotype for IGF-1 rs1520220 and high soy isoflavone intake tend to be associated with lower circulating IGF-1 levels synthetically (P = 0.002). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 5 | RESULTS: Among women aged less than 50 years, circulating IGF-1 serum levels were significantly lower for those with CC genotype for IGF-1 rs1520220 than levels for those with the GC or GG genotypes (in recessive model: P = 0.007).In gene-diet analyses among these women, we found carrying CC genotype for IGF-1 rs1520220 and high soy isoflavone intake tend to be associated with lower circulating IGF-1 levels synthetically (P = 0.002). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 6 | Women with GG or GC genotypes for IGF-1 rs1520220 and with low intake of soy isoflavones had the highest levels of circulating IGF-1 (geometric mean [95% CI]: 195 [37, 1021] microg/L). | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 7 | High soy isoflavone intake may interact with carrying CC genotype for IGF-1-rs1520220 to lower women"s serum IGF-1 levels more. | Isoflavones | insulin like growth factor 1 | Homo sapiens |
| 8 | High soy isoflavone intake may interact with carrying CC genotype for IGF-1-rs1520220 to lower women"s serum IGF-1 levels more. | Isoflavones | insulin like growth factor 1 | Homo sapiens |