Title : Topical rapamycin systematically suppresses the early stages of pulsed dye laser-induced angiogenesis pathways.

Pub. Date : 2014 Nov

PMID : 25270513






2 Functional Relationships(s)
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1 The phosphorylation levels of P70S6K increased after PDL exposure but those increases were suppressed by the topical RPM. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens
2 CONCLUSION: Topical application of 1% RPM can significantly and systematically suppress the PDL-induced early stage of angiogenesis via inhibition of the AKT/mTOR/P70S6K pathway in a rodent model. Sirolimus ribosomal protein S6 kinase B1 Homo sapiens