Title : O-GlcNAcylation and Metabolic Reprograming in Cancer.

Pub. Date : 2014

PMID : 25250015






2 Functional Relationships(s)
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1 Accumulating evidence suggests that O-GlcNAc transferase (OGT), an enzyme responsible for modification of proteins with N-acetylglucosamine, may act as a nutrient sensor that links hexosamine biosynthesis pathway to oncogenic signaling and regulation of factors involved in glucose and lipid metabolism. Hexosamines O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 Accumulating evidence suggests that O-GlcNAc transferase (OGT), an enzyme responsible for modification of proteins with N-acetylglucosamine, may act as a nutrient sensor that links hexosamine biosynthesis pathway to oncogenic signaling and regulation of factors involved in glucose and lipid metabolism. Hexosamines O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens