Title : C1q-mediated repression of human monocytes is regulated by leukocyte-associated Ig-like receptor 1 (LAIR-1).

Pub. Date : 2015 Feb 5

PMID : 25247291






1 Functional Relationships(s)
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1 In this study, we demonstrate that type 1 interferon (IFN) production by CpG-challenged monocytes can be suppressed by C1q through activating leukocyte-associated Ig-like receptor-1 (LAIR-1), which contains immunoreceptor tyrosine-based inhibition motifs (ITIMs). Tyrosine interferon alpha 1 Homo sapiens