Title : Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells.

Pub. Date : 2014 Dec

PMID : 25230779






1 Functional Relationships(s)
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1 Therefore, CD133 may inhibit 5-FU-induced apoptosis by regulating the expression of P-gp and Bcl-2 family mediated by phosphoinositide 3-kinase/Akt/p70S6K pathway in GC cells. Fluorouracil BCL2 apoptosis regulator Homo sapiens