Title : Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux.

Pub. Date : 2014 Oct 15

PMID : 25225670






1 Functional Relationships(s)
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Protein Name
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1 The nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 (Nlrp3) inflammasome plays an important role in inflammation by controlling the maturation and secretion of the cytokines IL-1beta and IL-18 in response to multiple stimuli including pore-forming toxins, particulate matter, and ATP. Adenosine Triphosphate interleukin 18 Homo sapiens