Title : The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme.

Pub. Date : 2014 Dec

PMID : 25224009






1 Functional Relationships(s)
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1 Furthermore, VT-1161 weakly inhibited human CYP2C9, CYP2C19, and CYP3A4, suggesting a low drug-drug interaction potential. VT-1161 cytochrome P450 family 3 subfamily A member 4 Homo sapiens