Pub. Date : 2014 Nov 5
PMID : 25218671
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Quantum chemical and steered molecular dynamics studies for one pot solution to reactivate aged acetylcholinesterase with alkylator oxime. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | Dimethyl(pyridin-2-yl)sulfonium based oxime has been designed to reverse the aging process of organophosphorus inhibited AChE and to reactivate the aged-AChE adduct. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | Dimethyl(pyridin-2-yl)sulfonium based oxime has been designed to reverse the aging process of organophosphorus inhibited AChE and to reactivate the aged-AChE adduct. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
4 | The free enzyme can be liberated from the inhibited acetylcholinesterase with the sulfonium compound decorated with an oxime group to avoid the administration of oxime drugs separately. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
5 | The free enzyme can be liberated from the inhibited acetylcholinesterase with the sulfonium compound decorated with an oxime group to avoid the administration of oxime drugs separately. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
6 | The computational study suggests that the newly designed oxime is a potential candidate to reactivate the aged-AChE adduct. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |