PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25218671-0 2014 Quantum chemical and steered molecular dynamics studies for one pot solution to reactivate aged acetylcholinesterase with alkylator oxime. Oximes 132-137 acetylcholinesterase (Cartwright blood group) Homo sapiens 96-116 25218671-1 2014 Dimethyl(pyridin-2-yl)sulfonium based oxime has been designed to reverse the aging process of organophosphorus inhibited AChE and to reactivate the aged-AChE adduct. Oximes 38-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 121-125 25218671-1 2014 Dimethyl(pyridin-2-yl)sulfonium based oxime has been designed to reverse the aging process of organophosphorus inhibited AChE and to reactivate the aged-AChE adduct. Oximes 38-43 acetylcholinesterase (Cartwright blood group) Homo sapiens 153-157 25218671-5 2014 The free enzyme can be liberated from the inhibited acetylcholinesterase with the sulfonium compound decorated with an oxime group to avoid the administration of oxime drugs separately. Oximes 119-124 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-72 25218671-5 2014 The free enzyme can be liberated from the inhibited acetylcholinesterase with the sulfonium compound decorated with an oxime group to avoid the administration of oxime drugs separately. Oximes 162-167 acetylcholinesterase (Cartwright blood group) Homo sapiens 52-72 25218671-12 2014 The computational study suggests that the newly designed oxime is a potential candidate to reactivate the aged-AChE adduct. Oximes 57-62 acetylcholinesterase (Cartwright blood group) Homo sapiens 111-115