Title : Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase.

Pub. Date : 2014 Nov 15

PMID : 25218290






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1 CONCLUSION: The lower susceptibility of female mice is achieved by the improved detoxification of reactive oxygen due to accelerated recovery of mitochondrial GSH levels, which attenuates late JNK activation and liver injury. reactive oxygen mitogen-activated protein kinase 8 Mus musculus